Dose of hepatitis vaccine in adults

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Usual Adult Dose for Hepatitis B Prophylaxis. Primary Vaccination: Engerix-B(R): Ages 19 and younger: Three doses (10 mcg each), IM, on a 0, 1, and 6 month schedule. Ages 20 and older: Three doses (20 mcg each), IM, on a 0, 1, and 6 month schedule. Recombivax-HB(R): Ages 19 and younger: Three doses (5 mcg each), IM, on a 0, 1, and 6 month schedule.

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During immunogenicity studies in adults, subjects with various forms of chronic hepatic disease had lower geometric mean antibody titers 1 month following dose 1 of the vaccine (ranging from milli-international units/ml for chronic hepatitis C patients to milli-international units/ml in .

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Dosage and Administration Schedule for VAQTA ® (Hepatitis A Vaccine, Inactivated) Adults (19 years of age and older): The vaccination schedule consists of a primary mL dose administered intramuscularly and a mL booster dose administered intramuscularly 6 to 18 months later.


The FDA has approved a two-dose hepatitis B virus (HBV) vaccine (Heplisav-B – Dynavax) for use in adults ≥18 years old. The three other HBV vaccines marketed in the US are usually administered in 3 doses. Engerix-B and Recombivax HB are licensed for use in persons of all ages. The shot is given in 2 doses — adults get each dose 6 to 18 months apart. You may be at risk for hepatitis A if you: Travel to a place where it’s common. Are a man who has sex with men. Use drugs (with or without needles) Are getting treatment for certain bleeding disorders, like hemophilia.
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Adults at increased risk for hepatitis B. Adults who are at risk for hepatitis B can also get vaccinated. The vaccine is given in 3 doses. The second dose is given 1 month after the first dose, followed by a third dose 6 months after the second dose.

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